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Table 3 Anti-malarial activity of the 80% rhizome extract of Kniphofia folosia in mice infected with Plasmodium berghei

From: In vivo anti-malarial activity of the hydroalcoholic extract of rhizomes of Kniphofia foliosa and its constituents

Test substances Dose (mg/kg/day) Percent parasitaemia Percent suppression Mean survival time (in days)
Vehicle1 0.2 ml 35.9860 ± 1.22034 0.0000 6.0000 ± 0.31623
KF100 100 mg 24.2100 ± 1.18037 32.7200a*c**d*e* 9.4000 ± 0.50990a**e*
KF200 200 mg 17.4920 ± 0.67964 51.3900a*b**e* 9.6000 ± 0.92736a*e*
KF400 400 mg 13.8480 ± 0.76024 61.5200a*b*e* 8.4000 ± 0.24495e*
Chloroquine 25 mg 0.0140 ± 0.00600 99.8000a* 27.2000 ± 0.58310a*b*c*d*
  1. Values are presented as mean ± SEM; n = 5; acompared to vehicle1 (distilled water), bcompared to KF100, ccompared to KF200, dcompared to KF400, ecompared to chloroquine; * (p < 0.001); **(p < 0.01); KF = 80% extracts of K. folosia, numbers refer to doses in mg/kg/day
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Malaria Journal

ISSN: 1475-2875

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