Pharmacokinetic profile of amodiaquine and its active metabolite desethylamodiaquine in Ghanaian patients with uncomplicated falciparum malaria

Table 3 Adverse events occurring within 28-days of artesunate-amodiaquine fixed dose combination treatment of uncomplicated falciparum malaria, by Intention-to-treat analysis

Adverse event	Number of patients reporting event n (%)
Pyrexia	25 (8.1)
Cough	21 (6.8)
Asthenia	16 (5.2)
Abdominal pain	13 (4.2)
Upper respiratory tract infection	11 (3.6)
Headache	7 (2.3)
Diarrhoea	7 (2.3)
Decreased appetite	5 (1.6)
Vomiting	4 (1.3)
Gastroenteritis	3 (0.97)
Pruritis	3 (0.97)
Peripheral swelling	3 (0.97)
Pain	2 (0.65)
Oral pain	2 (0.65)
Restlessness	2 (0.65)
Otorrhoea	2 (0.65)
Dysentery	2 (0.65)
Furuncle	2 (0.65)
Abdominal distension	1 (0.32)
Dyspnea	1 (0.32)
Rash	1 (0.32)
Total	136 (44.2)

ISSN: 1475-2875