Fig. 8

Isobologram of the co-administration of xylopic acid and artesunate, and xylopic acid and amodiaquine. Filled circles show theoretical ED₅₀ ± SEM, while open circles show experimental ED₅₀ ± SEM. The line of additivity connects the ED₅₀ of xylopic acid on the abscissa to that of artesunate and amodiaquine on the ordinate