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Table 3 Percentage parasitemia and chemosupression of mice treated with different doses of xylopic acid + amodiaquine combination for 5 days

From: Xylopic acid-amodiaquine and xylopic acid-artesunate combinations are effective in managing malaria in Plasmodium berghei-infected mice

Treatment (ED50 mg/kg) Dose (mg/kg) % Chem sup
Day 6
Sham 0.50 ml –
(XA/AQ)/16 0.6:0.2 41.2 ± 1.3
(XA/AQ)/8 1.125:0.4 43.9 ± 1.9
(XA/AQ)/4 2.25:0.8 56.4 ± 0.8
(XA/AQ)/2 4.5:1.6 68.4 ± 1.3
(XA/AQ) 12.1 9.0:3.1 79.8 ± 0.9
AL 1.14 – 88.3 ± 0.4
  1. Data are presented as mean ± SEM, (n = 5)
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Malaria Journal

ISSN: 1475-2875

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