Community acceptance of reactive focal mass drug administration and reactive focal vector control using indoor residual spraying, a mixed‐methods study in Zambezi region, Namibia

Table 1 2 × 2 factorial design of parent trial

	Human intervention
	RACD* (reactive case detection) 28 clusters	rfMDA^† (reactive focal mass drug administration) 28 clusters
Mosquito intervention
No RAVC	A	B
(no reactive focal vector control)	RACD only arm	rfMDA only arm
28 clusters	14 clusters	14 clusters
RAVC^‡	C	D
(reactive focal vector control)	RACD + RAVC arm	rfMDA + RAVC arm
28 clusters	14 clusters	14 clusters

*RACD (reactive case detection): administering rapid diagnostic tests to people living within a 500 m radius of an index case; treating positives with artemether-lumefantrine and single dose primaquine
^†rfMDA (reactive focal mass drug administration): presumptively treating individuals living within a 500 m radius around an index case using artemether-lumefantrine, without testing
^‡RAVC (reactive focal vector control): spraying long-acting insecticide, pirimiphos-methyl, on interior walls of sleeping structures in a 7-household radius around an index case

ISSN: 1475-2875