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|
Variant types
|
Single nucleotide polymorphism
|
Base substitution
|
Variant Frequency
|
Wild type
|
Status
|
Variant type
|
|---|
|
Wild type
|
–
|
–
|
–
|
241 (1)
|
–
|
WT
|
|
K189T
|
c.566A > C
|
AAA > ACA
|
1 [0.004]
|
240 [0.99]
|
–
|
NS
|
|
C469Y
|
c.1407C > G
|
TGC > TGG
|
1 [0.004]
|
240 [0.99]
|
Candidate
|
NS
|
|
M476I
|
c.1428G > T
|
ATG > ATT
|
3 [0.01]
|
238 [ 0.98]
|
Validated
|
NS
|
|
F483I
|
c.1447T > A
|
TTT > ATT
|
9 [0.04]
|
232 [0.96]
|
–
|
NS
|
|
S485N
|
c.1454G > A
|
AGT > AAT
|
7 [0.03]
|
234 [0.97]
|
–
|
NS
|
|
F491F
|
c.1473F > F
|
TTC > TTT
|
52 [0.22]
|
189 [0.78]
|
–
|
S
|
|
L492L
|
c.1476A > G
|
TTA > TTG
|
2 [0.01]
|
239 [0.99]
|
–
|
S
|
|
F506V
|
c.1516 T > G
|
TTT > GTT
|
8 [0.03]
|
232 [0.96]
|
–
|
NS
|
|
T508N
|
c.1523C > A
|
ACT > AAT
|
12 [0.05]
|
229 [0.95]
|
–
|
NS
|
|
S577L
|
c.1730S > L
|
TCA > TTA
|
13 [0.05]
|
228 [0.95]
|
–
|
NS
|
- NS nonsynonymous, S synonymous, [–] variants of unknown significance or not reported
- k13 variants that are either validated or are associated/candidates for ART resistance are shown
